OxyContin 80mg is a high-dose, extended-release oral tablet containing oxycodone hydrochloride, a potent semi-synthetic opioid analgesic used to manage severe, chronic pain. Because of its high strength, this specific dosage is strictly indicated for opioid-tolerant patients only Fatal Overdose Risk: If an individual who is not already tolerant to high-dose opioids takes this high-strength tablet, it can cause severe, fatal respiratory depression Do Not Crush or Chew: The tablet must be swallowed completely whole. Altering the tablet by breaking, chewing, crushing, or dissolving it disrupts the extended-release design. This leads to an immediate and dangerous absorption of the substance, which can be fatal